| Samedi 09 Octobre 2010 |
| Poule 1 | | 18:45 |  | Cardiff Blues | -
[ - ] | | |  | Edimbourg Rugby | -
[ - ] | |
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| Poule 2 | | 14:30 |  | Leinster | -
[ - ] | | |  | Racing-Metro 92 | -
[ - ] | |
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| | 16:30 |  | Clermont | -
[ - ] | | |  | Saracens | -
[ - ] | |
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| Poule 3 | | 14:30 |  | Toulon | -
[ - ] | | |  | Neath Swansea Ospreys | -
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| | 18:45 |  | London Irish | -
[ - ] | | |  | Munster | -
[ - ] | |
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| Poule 5 | | 14:30 |  | Trévise | -
[ - ] | | |  | Leicester Tigers | -
[ - ] | |
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| | 16:30 |  | Llanelli Scarlets | -
[ - ] | | |  | Perpignan | -
[ - ] | |
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